Nephrology Crosswords: Diabetic nephropathy

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Diabetic Nephropathy AGE, RAGE, and Diabetic Nephropathy

Diabetes is a disease that is present worldwide and which is associated with a large number of potential complications including chronic kidney disease (CKD). Several factors have been implicated in the development of the latter, including advanced glycation end-products (AGEs), which are formed from the interaction between sugar and proteins. AGE toxicity may be triggered via different mechani...

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Obstetric nephrology: pregnancy in women with diabetic nephropathy--the role of antihypertensive treatment.

This review highlights factors of importance for the clinical care of pregnant women with pregestational diabetes and microalbuminuria or diabetic nephropathy with particular focus on the role of intensive antihypertensive treatment during pregnancy. Most information in the literature comes from women with type 1 diabetes and diabetic nephropathy, but this is probably also valid for women with ...

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[Historical Archives of Italian Nephrology. Diabetic nephropathy and insulin discovery: two parallel histories].

In 1936, Kimmelstiel and Wilson described the nodular glomerulosclerosis in patients with diabetes mellitus on insulin treatment. The nodular glomerulosclerosis is referred to as diabetic nephropathy. Fifteen years earlier insulin was discovered. This discovery at the University of Toronto (Canada) in 1921-22 by Banting, Macleod, Best and Collip was one of the most dramatic events in the histor...

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Rosmarinic Acid Ameliorates Diabetic Nephropathy in Uninephrectomized Diabetic Rats

Objective(s) Oxidative stress plays an important role in diabetic nephropathy pathogenesis. Rosmarinic acid, a plant phenolic compound, was first used as an antioxidant agent for inhibition of diabetic nephropathy. Material and Methods Forty male rats were uninephrectomized from the left flank.The rats were divided in four groups randomly; group one as control, group two diabetic untreatment...

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Risk Factors for Diabetic Nephropathy in Diabetic Patients

Aims: Diabetic nephropathy is one of the consequences of type 1 and type 2 diabetes and one of the main causes of End-Stage Renal Disease (ESRD) as well as an important risk factor for cardiovascular morbidity and death. The aim of this study was to identify the risk factors for diabetic nephropathy in diabetic patients. Instruments & Methods: In this cross-sectional descriptive study, 121 pat...

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ژورنال

عنوان ژورنال: Kidney International

سال: 2015

ISSN: 0085-2538

DOI: 10.1038/ki.2015.8